Tyler Trent Pediatric Cancer Research Center

In creating the Tyler Trent Pediatric Cancer Research Center, the Purdue Institute for Cancer Research is assembling deep strengths in multiple research fields to fight pediatric cancers and to beat osteosarcoma, the rare bone cancer that took the life of beloved Purdue alumnus Tyler Trent.

A LEGACY OF IMPACT

Carrying the fight forward

The Tyler Trent Pediatric Cancer Research Center was established in 2023 at the Purdue Institute for Cancer Research (PICR) to focus on pediatric cancers, including osteosarcoma.

Scientific talent that is uniquely Purdue

When the Tyler Trent Pediatric Cancer Research Center was established, PICR Director Andrew Mesecar highlighted the power of Purdue’s collaboration among researchers in biochemistry, biological sciences, chemistry, computational sciences, engineering, medicinal chemistry, nutrition science, pharmacy, physical sciences, structural biology and veterinary medicine.

Targeting a rare form of childhood cancer

Dr. Michael Childress, the Evan and Sue Ann Werling Professor of Comparative Oncology in Purdue’s College of Veterinary Medicine, who has been studying osteosarcoma, will continue his work within the new Trent center.

“A third of patients diagnosed with osteosarcoma die from it, and these are mostly adolescents. That’s a real tragedy that speaks to the need to continue to push the envelope and look for new ways to improve the outlook for those patients,” Childress says.

Childress’ work targeting fundamental cancer mechanisms has the potential to contribute to the understanding of many forms of cancer and advance their therapies. He’s currently working on a prospective drug therapy to target a specific protein that helps drive the progression of osteosarcoma and several other cancers in dogs and humans. His findings hold the potential to advance therapies for those cancers.

United by a shared commitment to addressing childhood cancers, these scientists are shaping the future of research at the Tyler Trent Pediatric Cancer Research Center.

By Tony and Kelly Trent

Tyler’s parents remember their son’s inspirational life

Tyler Robert Trent was born on September 7, 1998, and sadly passed from this Earth due to osteosarcoma bone cancer on January 1, 2019. He was 20 years old. Tyler was known as an American cancer activist who attended Purdue University. He was diagnosed with osteosarcoma for the first time as a 15-year-old in 2014. He won the 2018 Disney Wide World of Sports Spirit Award as well as the 2018 Sagamore of the Wabash award, and his book, The Upset, with a foreword written by Scott Van Pelt and endorsed by icons in the sports world and other prominent leaders, became available in March 2019.

Tyler maintained a strong relationship with the Purdue football team and served as the honorary captain in both the 2017 and the 2018 Hammer Down Cancer games. He also served as honorary captain for the Music City Bowl game in Nashville, where Purdue played Auburn on December 28, 2018. He drew national attention with his College Game Day piece on ESPN with Tom Rinaldi. He predicted the Purdue Boilermakers would beat No. 2-ranked Ohio State and they did, 49-20. He even received shoutouts and phone calls from Vice President Mike Pence and Drew Brees. He went on to raise over a million dollars for cancer research.

A tattoo on Tyler Trent’s ankle paired a ribbon with a set of symbols that carried deep personal meaning — a representation of his perspective through highs and lows.

Tyler was an unlikely sports hero – a scrawny kid with a shy grin who dreamed of becoming a national sportswriter and statistician. He broke through the cluttered world of social media, inspiring a flood of support nationwide and demonstrating his passion for life, his passion for Purdue, and his passion to do whatever he could to raise awareness and money for cancer research, even in the midst of the crazy, horrible journey that he had been on. He just wanted to help people. He was a genuine, faith-filled, Christ-centered human being. There are several words that would describe Tyler: faithful, driven, determined, hardworking, self-sufficient, efficient, leader, magnetic, compassionate, helpful, others-oriented, brought people together, motivated and curious. These are a few that rise to the top of the list.

Tyler also volunteered with the Purdue Dance Marathon and served on the leadership team, which raises money for Riley Children’s Hospital and the Purdue Institute for Cancer Research, where he was the first student to ever sit on the board. He donated the tissue of his tumor for research, one of the first patients to do so at Riley Children’s Hospital. He also got the honor to name the tissue TT1 and TT2. Tyler’s heart was to do all he could for the entities and people and causes that were very personal and important to him. He was selfless in this position, not easy with the condition his health was in, but his spirit was always strong and fighting.

Tyler represented a son, brother, friend, nephew, cousin, grandson, activist and Boilermaker, among other things. When he was faced with the greatest adversity of his life, he leaned in, he never faltered. In his weakest moments he showed unimaginable strength. Tyler gave of himself, inspired others, faced long odds without fear knowing there is no failure if you give all you have. He inspired many with his faith in Christ, fearlessness and his fight.

It is said a Boilermaker will fight until there is no fight. While that’s not quite true, Tyler’s fight is over, but he will remain a Boilermaker forever.

Tyler Trent Cancer Research Endowment

The Tyler Trent Cancer Research Endowment, created in honor of beloved Purdue superfan Tyler Trent, will fund cancer research at the Purdue Institute for Cancer Research. Donations will generously be matched dollar-for-dollar by the Walther Cancer Foundation.

How you can help

Tyler’s parents, Tony and Kelly Trent, led the way to funding the cancer research center by donating $100,000 to continue the fight against cancer that Tyler began. With your generosity, you can join their campaign to beat this disease.

Contact Us

Get in touch

Phone: 765-494-9129
Fax: 765-494-9193
Email: cancerresearch@purdue.edu

Find us

201 S. University St.
Hansen Life Sciences Bldg, Rm. 141
West Lafayette, IN 47907