Seminar Series: Hana Hall
Hana Hall
Research Assistant Professor, Biochemistry
The Hana Hall lab investigates the molecular mechanisms underlying gene regulation during aging and neurodegeneration. We focus on how disruption in transcription and increased genome instability, driven by DNA damage, contribute to the onset and progression of age-associated disorders, such as Alzheimer’s disease. Specifically, we examine the role of chromatin architecture, including R-loops, and the impact of histone and RNA modifications on transcriptional and genomic integrity. To address these questions, we employ cutting-edge next-generation sequencing approaches, such as RNA-seq, CUT&RUN, and CUT&Tag, alongside fundamental biochemical and molecular biology techniques